General description

A cell-permeable retinoid-related molecule that induces tumor growth arrest and apoptosis. The exact molecular basis of the underlying mechanism(s) is not yet well understood, however, studies using ovarian adenocarcinoma cells have shown that CD437/AHPN effectively functions as an ER stress inducer.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Watanabe, Y., et al. 2008. Biochem. Biophys. Res. Comm.366, 840.Holmes, W.F., et al. 2004. J. Cell. Physiol.199, 317.Zhao, X., and Spanjaard, R.A. 2003. J. Biomed. Sci.10, 44.

Packaging

Packaged under inert gas

5 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 months at -20°C.

Warning

Toxicity: Carcinogenic / Teratogenic (D)